Enabling Next-Generation RNA-Based Therapeutics

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Your Partner in mRNA & LNP Design and Manufacturing

Co-founded in 2022 by leading scientists, including Nobel Laureate Dr. Drew Weissman and Dr. Mohamad-Gabriel Alameh.

At RNA Technologies & Therapeutics (RTT), we leverage our unique expertise to consistently manufacture & deliver high-quality, cost-effective mRNA and lipid nanoparticle (LNP) products. Our flexible RUO and GMP solutions span from mRNA design and optimization to LNP formulation, accelerating innovative RNA therapeutics from early research through Phase I/II clinical trials. 

We are dedicated to ensuring that breakthrough therapeutics in rare diseases, personalized cancer vaccines, and cell and gene therapies remain affordable and accessible to patients who need them.

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Our expertise

High quality, highly expressed mRNA

Advanced sequence and UTR optimization & custom mRNA design, synthesis, purification and analytics for research through Phase I/II clinical trials. 

LNP formulations

LNP formulation, mRNA encapsulation, process optimization, and manufacturing of targeted and non-targeted LNPs.

Cost-effective research & clinical manufacturing

Flexible RUO and GMP manufacturing supporting research and early clinical programs. End-to-end services, spanning design, manufacturing and QC testing.

The science behind breakthrough therapies

RTT utilizes the same mRNA optimization platform and technical know-how that helped to develop the world’s first personalized gene-editing therapy used to successfully treat Baby KJ. 

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Acuitas Therapeutics

STRATEGIC PARTNERSHIP

Having worked extensively with RTT over the last number of years, we are impressed with their scientific approach and technical know-how which brings a level of precision and consistency that is critical in RNA drug development. Ultimately, this investment gives our partners a coordinated way to engage experts from both companies as they develop the next-generation RNA-LNP therapies
Dr Thomas Madden-CEO

Off-the-shelf optimized mRNA
(Partial list) 

Full list Off-the-shelf products

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Gene editing and genome engineering

  • ABE8.8m
  • ABE8e
  • co.xCAS9
  • ...

Reporters and imaging

  • FLuc
  • eGFP
  • mCherry
  • Neptune
  • Cardinal
  • ...

In vivo cell and gene therapies

Multiple species

  • CD19
  • CD20
  • ...

Antigens

Cancer and infectious diseases, and neoepitopes

  • OVA
  • Wuhan CoV-2 RBD
  • RSV-F
  • ...

Immunomodulators

  • hCSF3
  • IL-1
  • IL-12
  • ...

Others

  • hEPO
  • FGF21
  • ...

A new RTT experience is coming soon

We are developing a new website featuring an expanded portfolio of ready-to-use mRNA and LNP products for gene editing, cell engineering and preclinical research, with streamlined online ordering.

We remain fully operational and ready to support your projects.

Let's work together

Contact us to explore our off-the-shelf mRNA and LNP products, discuss custom mRNA and LNP manufacturing projects, or request a quote.